Rhyse Martin, Chris Smith and Ofahiki Ogden are the new faces on the bench for the clash with the Tigers.
Pay is the only coach making sweeping changes this week, though other clubs will welcome the timely return of some familiar faces from injury.
Manly fans will be happy to see Tom Trbojevic named at fullback for their clash with the Warriors. He has recovered from an ankle injury, with Addin Fonua-Blake also returning from suspension.
Cooper Cronk and Jake Friend come back into the Roosters side which breezed past Manly, triggering a shuffle which will push Victor Radley back to lock, Angus Crichton back to the bench and Lachlan Lam out of the 17 altogether.
Josh Mansour is back in the starting side after being a late omission from Penrith’s win over Newcastle, pushing Malakai Watene-Zelezniak out of the team.
Consecutive concussions have kept Isaah Yeo out of the Panthers team, with Frank Winterstein to have his place in the starting side.
Cowboys coach Paul Green has switched the shape of his spine, with Te Maire Martin switching from five-eighth to fullback and youngster Jake Clifford getting his chance in the No. 6 jersey.
Centres Justin O’Neill and Tom Opacic have both been dropped. Ben Hampton and Jordan Kahu will replace the pair. Coen Hess is the man charged with replacing the sizeable hole left by Jason Taumololo.